Manufactured by:BT LAB
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Ribosomal Protein S6(Phospho Ser240) Polyclonal Antibody

Ribosomal Protein S6(Phospho Ser240) Polyclonal Antibody

SKU:
ABM192704
Manufacturer SKU
BT-AP13802
Product type
Primary Antibodies
TargetRPS6
ApplicationsWB, IHC-P, IF/ICC, ELISA
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling
Also known as
40S ribosomal protein S6; RPS6; OK/SW-cl.2; 40S ribosomal protein S6; Phosphoprotein NP33
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 100 - 1: 300; IF: 1: 200 - 1: 1000; ICC: 1: 200 - 1: 1000; ELISA: 1: 5000
Immunogen
The antiserum was produced against synthesized peptide derived from human S6 Ribosomal Protein around the phosphorylation site of Ser240. AA range:200-249
Molecular weight
28681
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pIFICCELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP13802
Gene ID
6194
UniProt accession
P62753
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

RPS6ribosomal protein S6

View target guide

RPS6 identifies ribosomal protein S6 in Homo sapiens (Human). This target record connects NCBI Gene 6194, UniProtKB P62753 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
6194
UniProtKB
P62753
BT LAB
£81.31£69.00