Manufactured by:BT LAB
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PON1 Polyclonal Antibody

PON1 Polyclonal Antibody

SKU:
ABM190979
Manufacturer SKU
BT-AP13226
Product type
Primary Antibodies
TargetPON1
ApplicationsIHC-P, ELISA, IF/ICC
Species / reactivityHuman, Rat, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

Key facts & specifications
Research areas
Cardiovascular, Cell Biology, Metabolism, Neuroscience, Signal Transduction
Also known as
Serum paraoxonase/arylesterase 1 ;PON 1;EC 3.1.1.2;EC 3.1.1.81;EC 3.1.8.1;Aromatic esterase 1;A-esterase 1;K-45;Serum aryldialkylphosphatase 1; Serum paraoxonase/arylesterase 1; PON 1; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; Aromatic esterase 1; A-esterase 1; K-45; Serum aryldialkylphosphatase 1
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
IHC-p: 1: 50 - 1: 200; ELISA: 1: 10000 - 1: 20000
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PON1. AA range:51-100
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP13226
Gene ID
5444
UniProt accession
P27169
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PON1paraoxonase 1

View target guide

PON1 identifies paraoxonase 1 in Homo sapiens (Human). This target record connects NCBI Gene 5444, UniProtKB P27169 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5444
UniProtKB
P27169
BT LAB
£81.31£69.00