Manufactured by:BT LAB
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OREX Polyclonal Antibody

OREX Polyclonal Antibody

SKU:
ABM188996
Manufacturer SKU
BT-AP12549
Product type
Primary Antibodies
TargetHCRT
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.

Key facts & specifications
Research areas
Metabolism, Neuroscience
Also known as
Orexin ;Hypocretin;Hcrt [Cleaved into: Orexin-A ;Hypocretin-1;Hcrt1; Orexin-B ;Hypocretin-2;Hcrt2]
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; ELISA: 1: 5000 - 1: 20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 21-70
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP12549
Gene ID
3060
UniProt accession
O43612
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

HCRThypocretin neuropeptide precursor

View target guide

HCRT identifies hypocretin neuropeptide precursor in Homo sapiens (Human). This target record connects NCBI Gene 3060, UniProtKB O43612 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
3060
UniProtKB
O43612
BT LAB
£81.31£69.00