Manufactured by:BT LAB
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CHIP Polyclonal Antibody

CHIP Polyclonal Antibody

SKU:
ABM174457
Manufacturer SKU
BT-AP07666
Product type
Primary Antibodies
TargetSTUB1
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling
Also known as
E3 ubiquitin-protein ligase CHIP ;EC 6.3.2.-;Antigen NY-CO-7;CLL-associated antigen KW-8;Carboxy terminus of Hsp70-interacting protein;STIP1 homology and U box-containing protein 1
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; ELISA: 1: 5000 - 1: 20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP07666
Gene ID
10273
UniProt accession
Q9UNE7
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

STUB1STIP1 homology and U-box containing protein 1

View target guide

STUB1 identifies STIP1 homology and U-box containing protein 1 in Homo sapiens (Human). This target record connects NCBI Gene 10273, UniProtKB Q9UNE7 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
10273
UniProtKB
Q9UNE7
BT LAB
£81.31£69.00