Manufactured by:BT LAB
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p70 S6 kinase Alpha Polyclonal Antibody

p70 S6 kinase Alpha Polyclonal Antibody

SKU:
ABM172090
Manufacturer SKU
BT-AP06858
Product type
Primary Antibodies
TargetRPS6KB1
ApplicationsWB, IF/ICC, IHC-P
Species / reactivityMouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

RPS6KB1 (ribosomal protein S6 kinase B1) encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of RPS6KB1 has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for RPS6KB1 on chromosome 17.

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Key facts & specifications
Research areas
Cell Biology
Also known as
RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 1000 - 2000; IF: 1: 50 - 200
Immunogen
Recombinant Protein of p70 S6 kinase α
Molecular weight
59140
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIFIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP06858
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

RPS6KB1ribosomal protein S6 kinase B1

View target guide

RPS6KB1 identifies ribosomal protein S6 kinase B1 in Homo sapiens (Human). This target record connects NCBI Gene 6198, UniProtKB P23443 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
6198
UniProtKB
P23443
BT LAB
£81.31£69.00