Manufactured by:BT LAB
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Nrf2 Polyclonal Antibody

Nrf2 Polyclonal Antibody

SKU:
ABM170152
Manufacturer SKU
BT-AP06175
Product type
Primary Antibodies
TargetNFE2L2
ApplicationsWB, IHC-P
Species / reactivityHuman, Rat, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

NFE2L2 encodes a transcription factor (nuclear factor, erythroid 2 like 2) which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for NFE2L2.

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling
Also known as
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 50 - 300
Immunogen
Synthesized peptide derived from human Nrf2 around the non-acetylation site of K599.
Molecular weight
75-100
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP06175
Gene ID
4780
UniProt accession
Q16236
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

NFE2L2NFE2 like bZIP transcription factor 2

View target guide

NFE2L2 identifies NFE2 like bZIP transcription factor 2 in Homo sapiens (Human). This target record connects NCBI Gene 4780, UniProtKB Q16236 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4780
UniProtKB
Q16236
BT LAB
£81.00£69.00