Adrenocorticotropin(ACTH) Polyclonal Antibody
Know who made it. See the evidence. Buy through one marketplace.
This gene encodes a preproprotein that undergoes extensive| tissue-specific| post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and| depending on tissue type and the available convertases| processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin| essential for normal steroidogenesis and the maintenance of normal adrenal weight| and lipotropin beta are the major end products. In other tissues| including the hypothalamus| placenta| and epithelium| all cleavage sites may be used| giving rise to peptides with roles in pain and energy homeostasis| melanocyte stimulation| and immune modulation. The
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | WB | IHC-p | IF |
|---|---|---|---|
| Applications |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
POMC identifies proopiomelanocortin in Homo sapiens (Human). This target record connects NCBI Gene 5443, UniProtKB P01189 and related ABMIUM catalogue products.
