Manufactured by:BT LAB
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Tau(Phospho Thr231) Polyclonal Antibody

Tau(Phospho Thr231) Polyclonal Antibody

SKU:
ABM156786
Manufacturer SKU
BT-AP01701
Product type
Primary Antibodies
TargetMAPT
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex| regulated alternative splicing| giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system| depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease| Pick's disease| frontotemporal dementia| cortico-basal degeneration and progressive supranuclear palsy.

Key facts & specifications
Research areas
Neuroscience, Signal Transduction
Also known as
Microtubule-associated protein tau; MAPT; MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; ELISA: 1: 10000
Immunogen
The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Thr231.
Molecular weight
78746
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP01701
Gene ID
4137
UniProt accession
P10636
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MAPTmicrotubule associated protein tau

View target guide

MAPT identifies microtubule associated protein tau in Homo sapiens (Human). This target record connects NCBI Gene 4137, UniProtKB P10636 and related ABMIUM catalogue products.

Biological function: MAPT encodes tau, a microtubule-associated protein that promotes microtubule assembly and stability and contributes to establishment and maintenance of neuronal polarity.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4137
UniProtKB
P10636
BT LAB
£81.00£69.00