ABMIUM target intelligence
serpin family E member 1
Serpin family E member 1 (SERPINE1), commonly called plasminogen activator inhibitor 1 (PAI-1), is a serine-protease inhibitor. This ABMIUM record links human SERPINE1 (NCBI Gene 5054; UniProt P05121) to catalogue-backed research products.
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Research context & evidence
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SERPINE1/PAI-1 is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), making it an important inhibitor of fibrinolysis. Curated records also describe a role in innate antiviral immunity.
SERPINE1, PAI-1 and plasminogen activator inhibitor 1 are widely studied in fibrinolysis, thrombosis, vascular biology and extracellular protease regulation. Confirm product-level species, application and validation before use.
Names used across publications, databases and supplier catalogues.
