ERBB2Functional association
UniProt reports ligand-induced EGFR heterodimerisation with ERBB2.
ABMIUM target intelligence
epidermal growth factor receptor
EGFR identifies epidermal growth factor receptor in Homo sapiens (Human). This target record connects NCBI Gene 1956, UniProtKB P00533 and related ABMIUM catalogue products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
EGFR is a receptor tyrosine kinase that binds EGF-family ligands and converts extracellular growth signals into intracellular signalling responses. Ligand binding promotes receptor dimerisation and autophosphorylation, activating pathways that regulate cell proliferation, survival, differentiation and migration.
EGFR is widely studied in growth-factor signalling, receptor trafficking and cancer biology. Use the catalogue filters below to compare ABMIUM reagents by species, application and validation, and confirm product-level suitability before use.
Names used across publications, databases and supplier catalogues.
These relationships provide research context only. They do not establish product or application suitability.
UniProt reports ligand-induced EGFR heterodimerisation with ERBB2.
UniProt reports GRB2 binding to activated EGFR to couple the receptor to downstream signalling.
UniProt reports interaction with CBL in EGFR ubiquitination and regulation.
Interpretation: Identity and identifiers were checked against NCBI and reviewed UniProtKB. Biological function and listed interactions are conservatively paraphrased from UniProt evidence. Catalogue association does not establish suitability for a specific assay.