ABMIUM target intelligence
B and T lymphocyte associated
BTLA (B and T lymphocyte associated), commonly called B- and T-lymphocyte attenuator or CD272, is an inhibitory lymphocyte receptor studied in antigen-receptor signalling and adaptive immune regulation.
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Names used across publications, databases and supplier catalogues.
BTLA is a cell-surface inhibitory receptor that attenuates antigen-receptor signalling through the phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. Reviewed human evidence also supports cis and trans interactions with TNFRSF14/HVEM, placing BTLA in regulatory circuits that tune lymphocyte activation and resting state.
BTLA/CD272 is studied in T- and B-cell activation, inhibitory receptor signalling, immune checkpoints and adaptive immune regulation. Abmium products linked below should be selected by species, sample type, assay format, application and product-level validation.