ABMIUM target intelligence

BTLA

B and T lymphocyte associated

BTLA (B and T lymphocyte associated), commonly called B- and T-lymphocyte attenuator or CD272, is an inhibitory lymphocyte receptor studied in antigen-receptor signalling and adaptive immune regulation.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene151888 UniProtQ7Z6A9

BTLA products

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Anti-CD272/BTLA Antibody Picoband® Boster Bio
Boster BioABMIUM Verified™

Anticorps Anti-CD272/BTLA Picoband®

SKU: ABM22473-1Anticorps primaires
Target
Atténuateur de lymphocytes B et T
Reactivity
Humain,Souris
Applications
ELISA,Cytoflométrie en flux,IF/ICC,IHC,IHC-F,IHC-P,WB
Host
Lapin
From£278.80£328.00 Save 15%
Available to order
Comparing

Research context & evidence

About BTLA

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

BTLA is a cell-surface inhibitory receptor that attenuates antigen-receptor signalling through the phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. Reviewed human evidence also supports cis and trans interactions with TNFRSF14/HVEM, placing BTLA in regulatory circuits that tune lymphocyte activation and resting state.

Experimental context

Research context

BTLA/CD272 is studied in T- and B-cell activation, inhibitory receptor signalling, immune checkpoints and adaptive immune regulation. Abmium products linked below should be selected by species, sample type, assay format, application and product-level validation.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

CD272B- and T-lymphocyte attenuatorBTLA1A630002H24B- and T-lymphocyte-associated protein