Manufactured by:BT LAB
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Human Interleukin 37, IL-37 ELISA Kit

Human Interleukin 37, IL-37 ELISA Kit

SKU:
ABM211340
Manufacturer SKU
E1947Hu
Product type
ELISA Kits
TargetIL37
ApplicationsELISA
Species / reactivityHuman
Sample typeSerum, Plasma, Cell culture supernatants, Ascites, Tissue homogenates

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

Test principle

This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Human IL37 antibody. IL37 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human IL37 Antibody is added and binds to IL37 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated IL37 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human IL37. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
Key facts & specifications
Research areas
Immunology
Also known as
FIL1 zeta;IL 37;IL-1 zeta;IL-1F7;IL-1H;IL-1H4;IL-1RP1;IL-1X;IL-23;IL37;IL-37;Interleukin-1 family member 7;Interleukin-1 homolog 4;Interleukin-1 zeta;Interleukin-1-related protein;Interleukin-23;Interleukin-37
Assay type
Sandwich
Detection method
Colorimetric (450 nm)
Sensitivity
4.56ng/L
Detection range
7-400ng/L
Plate format
Pre-coated ELISA plate
Assay duration
1h 30m
Molecular weight
24,126 Da
Quantity per pack
48T, 96T
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceSerumPlasmaCell culture supernatantsAscitesTissue homogenates
Compatibility
Identifiers & database references
Manufacturer SKU
E1947Hu
Gene symbol
IL37
Gene ID
27178
UniProt accession
Q9NZH6
Storage, stability & shipping
Shelf life
Store at -20°C for one year. Or store at 2-8°C for 6 months. If individual reagents are opened it is recommended that the kit be used within 1 month. Avoid repeated thaw cycles. *This product is for research use only, not for use in diagnosis procedures. It’s highly recommended to read this instruction entirely before use.
Storage conditions
2-8ºC
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

IL37interleukin 37

View target guide

IL37 identifies interleukin 37 in Homo sapiens (Human). This target record connects NCBI Gene 27178, UniProtKB Q9NZH6 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
27178
UniProtKB
Q9NZH6
BT LAB
£240.93£205.00