Inicio » BCL2L1 Bcl-2-Like Protein 1 (Bcl-xL) | ABMIUM

ABMIUM target intelligence

BCL2L1

BCL2 like 1

BCL2 like 1 (BCL2L1) encodes Bcl-2-like protein 1, whose major splice isoforms include anti-apoptotic Bcl-xL and pro-apoptotic Bcl-xS. This BCL-2-family regulator is central to mitochondrial apoptosis and cell-survival research.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene598 UniProtQ07817

BCL2L1 products

Need help?Ask a scientist
Loading… products
Anti-Bcl-XL/BCL2L1 Antibody Picoband® Boster Bio
Boster BioABMIUM Verified™

Anti-Bcl-XL/BCL2L1 Antibody Picoband®

SKU: ABM21642-1Primary Antibodies
Target
Bcl-2-like protein 1
Host
Rabbit
Clonality
Polyclonal
Reactivity
Human, Mouse, Rat
Applications
ELISA, Flow Cytometry, IF/ICC, IHC, IHC-P, IP, WB
From£278.80£328.00 Save 15%
Available to order
Choose options
Comparing

Research context & evidence

About BCL2L1

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

BCL2L1 produces Bcl-2-like protein 1 isoforms with opposing effects on apoptosis. Bcl-xL inhibits cell death by limiting mitochondrial cytochrome-c release and caspase activation, whereas Bcl-xS promotes apoptosis. The reviewed human protein is also implicated in cell-cycle checkpoint regulation.

Experimental context

Research context

BCL2L1 / Bcl-xL is widely studied in intrinsic apoptosis, mitochondrial cell-death signalling, BCL-2-family biology and cancer models. Interpret reagent results in light of isoform specificity, epitope or clone, species, sample type, assay format and product-level validation.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Bcl-2-like protein 1Bcl2LBCL-xB2CL1BCL-XL/SPPP1R52blp1cb1021zfBLP1Bcl-X(L)Bcl-xLBcl-X(S)Bcl-xS