ElabscienceABMIUM Verified™
Anti-Human ATG4A Antibody
SKU: ABM5431-1Primary Antibodies
- Target
- ATG4A
- Host
- Rabbit
- Clonality
- Polyclonal
- Reactivity
- Human
- Applications
- WB, IHC
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Available to orderABMIUM target intelligence
autophagy related 4A cysteine peptidase
ATG4A (autophagy related 4A cysteine peptidase), also called cysteine protease ATG4A or autophagin-2, is an ATG4-family cysteine protease that regulates ATG8-family protein processing during macroautophagy.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ATG4A is a peptidase family C54 cysteine protease involved in the proteolytic processing of ATG8-family proteins. ATG4-family enzymes expose the C-terminal glycine needed for ATG8 lipidation and can reverse lipidation, helping regulate autophagosome membrane dynamics and autophagic flux.
ATG4A is studied as a regulator of macroautophagy, including ATG8-family processing, autophagosome maturation and autophagic flux. Experimental interpretation should consider overlapping ATG4-family activity, cell context and the specific ATG8-family substrate or assay used.
Names used across publications, databases and supplier catalogues.