ABMIUM target intelligence

TNFRSF1B

TNF receptor superfamily member 1B

TNFRSF1B identifies TNF receptor superfamily member 1B in Homo sapiens (Human). This target record connects NCBI Gene 7133, UniProtKB P20333 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene7133 UniProtP20333

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Tumor necrosis factor receptor superfamily member 1BTNF RIITNF-R2CD120bTBPIITNF-R75TNFBRTNFR1BTNFR80TNR1Bp75p75TNFRTNF-alphaR2Tnfr-1

Biological function

TNFRSF1B (TNFR2) is a high-affinity receptor for TNF. Its signalling recruits TRAF proteins and associated survival regulators and contributes to TNF-dependent cellular and metabolic responses.

Research context

TNFRSF1B is studied in TNF signalling, immune-cell regulation, cell survival and inflammatory responses, including biology distinct from TNFRSF1A/TNFR1.