TargetVEGFR2/CD309/KDRPurity>95% by SDS-PAGEMol. weight110 kDaActivityImmobilized mouse VEGF164 at 10 μg/ml (100 μl/well) can b...SpeciesRat
Immobilized mouse VEGF164 at 10 μg/ml (100 μl/well) can bind rat KDR-FcThe EC50 of rat KDR-Fc is 0.07-0.15 μg/ml.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.
TargetVEGFR2/Flk-1/KDRPurity>78% by SDS-PAGEMol. weight89.3 kDaActivityThe specific activity was determined to be 10 nmol/min/mg...SpeciesHuman
The specific activity was determined to be 10 nmol/min/mg using Poly(GluTyr) 4:1 as substrate.Baculovirus-Insect Cells< 1.0 EU per μg of the protein as determined by the LAL method.
TargetVEGFR2/Flk-1/KDRPurity>90% by SDS-PAGEMol. weight110 kDaActivityImmobilized mouse VEGF164 at 10 μg/ml (100 μl/well) can b...SpeciesMouse
Immobilized mouse VEGF164 at 10 μg/ml (100 μl/well) can bind mouse KDR-FcThe EC50 of mouse KDR-Fc is 0.11-0.27 μg/ml.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.
TargetVEGFR2/Flk-1/KDRPurity>90% by SDS-PAGEMol. weight109 kDaActivity1. Immobilized recombinant human VEGFA at 1. 25 μg/ml (10...SpeciesHuman
1. Immobilized recombinant human VEGFA at 1. 25 μg/ml (100 μl/well) can bind VEGFR2 with a linear range of 1.25-40.0 ng/ml. 2. Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 20-120 ng/mL in the presence of 10 ng/mL recombinant human VEGF165.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.
TargetVEGFR2/Flk-1/KDRPurity>97% by SDS-PAGEMol. weight84.6 kDaActivity1. Using the Octet RED System, the affinity constant (Kd)...SpeciesHuman
1. Using the Octet RED Systemthe affinity constant (Kd) of human VEGFR2-his bound to biotinylated human VEGF165 was 5.9nM. 2. Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells(HUVEC). The ED50 for this effect is typically 10-50μg/mL in the presence of 10 ng/mL recombinant human VEGF165.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.
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