TargetFLT1Purity>90% by SDS-PAGEMol. weight35.6 kDaActivityMeasured by its ability to inhibit the VEGF-dependent pro...SpeciesHuman
Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells ( HUVEC ). The ED50 for this effect is typically 10-40 ng/mL in the presence of 10 ng/mL human VEGF165.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.
TargetFLT1Purity>97% by SDS-PAGEMol. weight83.7 kDaActivityMeasured by its ability to inhibit the VEGF-dependent pro...SpeciesHuman
Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC)The ED50 for this effect is typically 10-40 ng/mL in the presence of 10 ng/mL human VEGF165.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.
TargetVEGFR1/FLT-1Purity>90% by SDS-PAGEMol. weight84.0 kDaActivityMeasured by its ability to inhibit VEGF-dependent prolife...SpeciesRat
Measured by its ability to inhibit VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 15-70ng/mL in the presence of 10 ng/mL rmVEGF164.HEK293 Cells< 1.0 EU per μg of the protein as determined by the LAL method.
