ABMIUM target intelligence
interleukin 1 receptor type 1
Interleukin-1 receptor type 1 (IL1R1), also known as CD121A and IL-1R1, is a cell-surface receptor for interleukin-1 family ligands. This ABMIUM record connects NCBI Gene 3554 and UniProtKB P14778 to catalogue-backed research products.
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Research context & evidence
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Interleukin-1 receptor type 1 (IL1R1/CD121A) binds IL-1 alpha, IL-1 beta and the interleukin-1 receptor antagonist. Ligand-dependent receptor complex formation recruits signalling adaptors and activates pathways including NF-kappaB and MAPK, making IL1R1 a central component of IL-1 inflammatory signalling.
IL1R1 is studied in interleukin-1 signalling, innate immunity, inflammation and cytokine-response pathways. Use the linked ABMIUM research products to investigate IL-1 receptor biology, confirming species, sample type, assay format, application and product-level validation.
Names used across publications, databases and supplier catalogues.
