![Anti-Human CD80 Antibody [2F4] - ABMIUM](http://www.abmium.com/cdn/shop/files/m54te9.jpg?v=1781559420&width=520)
ElabscienceABMIUM Verified™
Anti-Human CD80 Antibody [2F4]
SKU: ABM94-1Primary Antibodies
- Target
- CD80
- Host
- Mouse
- Clonality
- Monoclonal
- Reactivity
- Human
- Applications
- Flow Cytometry
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CD80 molecule
CD80 molecule (CD80), also known as B7-1 and T-lymphocyte activation antigen CD80, is an immunoglobulin-superfamily costimulatory molecule. This guide connects human NCBI Gene 941, UniProtKB P33681 and ABMIUM catalogue products associated with CD80.
Read full target overview
![Raji were stained with 0.2 μg AF/LE Purified Anti-Human CD80 Antibody[2D10] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by Elab Fluor<sup>®</sup> 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.](http://www.abmium.com/cdn/shop/files/luSpD8.jpg?v=1781594808&width=520)
Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
CD80 / B7-1 provides an important costimulatory signal for T-lymphocyte activation by acting as a ligand for CD28, augmenting MHC/T-cell receptor signalling. CD80 also binds CTLA-4, which can oppose CD28-mediated priming and limit T-cell activation, placing CD80 at a key immune costimulation and checkpoint interface.
CD80 / B7-1 is commonly studied in antigen-presenting-cell biology, T-cell costimulation, CD28 and CTLA-4 signalling, humoral immunity and immune-oncology models. Use the catalogue filters below to compare ABMIUM CD80 research products and confirm species, assay format, application and product-level validation before use.
Names used across publications, databases and supplier catalogues.