ABMIUM target intelligence

CASP9

caspase 9

CASP9 identifies caspase 9 in Homo sapiens (Human). This target record connects NCBI Gene 842, UniProtKB P55211 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene842 UniProtP55211

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Caspase-9APAF-3ICE-LAP6MCH6PPP1R56im:7136887zgc:101776Casp9_v1

Biological function

CASP9 is an initiator cysteine protease in the intrinsic apoptotic pathway. Following cytochrome-c-dependent apoptosome assembly with APAF1, procaspase-9 is activated and helps initiate the downstream caspase cascade.

Research context

CASP9 is widely studied in mitochondrial apoptosis, apoptosome signalling, programmed cell death, stress responses and cancer models. Reagent selection should consider cleavage or activation state, species, sample type, assay format, application and supporting validation.