Anticorps primaire fourni par Boster Bio
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DARS2 contient des résidus conservés impliqués dans la liaison de l'ATP, la liaison de l'ARNt et la reconnaissance de l'acide aspartique, ainsi que des motifs de site catalytique caractéristiques des aminoacyl-ARNt synthétases. La protéine codée par ce gène appartient à la famille des aminoacyl-ARNt synthétases de classe II. C'est une enzyme mitochondriale qui aminoacyle spécifiquement l'aspartyl-ARNt. Les mutations de ce gène sont associées à une leucoencéphalopathie avec atteinte du tronc cérébral et de la moelle épinière et une élévation du lactate (LBSL). L'International Radiation Hybrid Mapping Consortium a cartographié le gène DARS2 sur le chromosome 1.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Espèce | WB | IHC | IHC-P | IHC-F | IF/ICC | Cytométrie en flux | ELISA | IP |
|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.