ABMIUM target intelligence

SELE

selectin E

SELE identifies selectin E in Homo sapiens (Human). This target record connects NCBI Gene 6401, UniProtKB P16581 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene6401 UniProtP16581

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

E-selectinCD62EELAMELAM1ESELLECAM2LYAM2selectin-e

Biological function

SELE (E-selectin/CD62E) is an endothelial cell-surface adhesion glycoprotein that supports neutrophil adhesion to cytokine-activated endothelium, including through recognition of SELPLG/PSGL1.

Research context

SELE is studied in endothelial activation, leukocyte tethering and rolling, neutrophil recruitment and vascular inflammatory responses.