ABMIUM target intelligence

CXCL8

C-X-C motif chemokine ligand 8

CXCL8 identifies C-X-C motif chemokine ligand 8 in Homo sapiens (Human). This target record connects NCBI Gene 3576, UniProtKB P10145 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene3576 UniProtP10145

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

IL-8Interleukin-8GCP-1LECTLUCTLYNAPMDNCFMONAPNAFNAP-1SCYB8AMCF-ICEF4EMF1

Biological function

CXCL8 (IL-8) is a chemokine that drives inflammatory leukocyte recruitment, particularly neutrophil chemotaxis and activation, through the receptors CXCR1 and CXCR2.

Research context

CXCL8 is studied in neutrophil recruitment and activation, inflammatory signalling, infection responses and CXCR1/CXCR2 chemokine-receptor biology.