ABMIUM target intelligence

BST2

bone marrow stromal cell antigen 2

BST2 (bone marrow stromal cell antigen 2), also known as tetherin, CD317 and HM1.24, is an interferon-inducible membrane protein studied as a cell-intrinsic antiviral restriction factor and marker of innate immune activation.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene684 UniProtQ10589

BST2 products

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Anti-BST2 Monoclonal Antibody Boster Bio
Boster BioABMIUM Verified™

Anticorps monoclonal anti-BST2

SKU: ABM29350Anticorps primaire
Target
Antigène stromale 2 de la moelle osseuse
Reactivity
Humain
Applications
Cytométrie en flux, IHC, WB
Host
Lapin
£278.80£328.00 Save 15%
Available to order
Comparing

Research context & evidence

About BST2

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

BST2/tetherin restricts the release of diverse enveloped viruses by physically tethering nascent virions to infected-cell membranes. Its unusual membrane anchoring enables retained virions to remain at the surface or undergo endocytic internalization, linking BST2 to antiviral restriction, membrane trafficking and interferon-responsive host defence.

Experimental context

Research context

BST2 is used in research on interferon-stimulated antiviral defence, host-virus interactions, membrane trafficking and innate immune signalling. Abmium catalogue products linked below provide target-specific starting points; species, sample type, assay format, application and product-level validation should be checked for each reagent.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Bone marrow stromal antigen 2TetherinCD317HM1.242310015I10RikDAMP-1GREGBST-2HM1.24 antigenNPC-A-7antiviral factor tetherin