ABMIUM target intelligence

APC

APC regulator of Wnt signaling pathway

APC (APC regulator of Wnt signaling pathway; adenomatous polyposis coli protein) is a multifunctional tumour-suppressor scaffold best known for restraining canonical Wnt signalling by promoting beta-catenin turnover.

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OrganismHomo sapiens (Human) NCBI Gene324 UniProtP25054

APC products

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Anti-APC Monoclonal Antibody Boster Bio
Boster BioABMIUM Verified™

Anticorps monoclonal anti-APC

SKU: ABM29300Anticorps Primaire
Target
Protéine de la polypose adénomateuse du côlon
Reactivity
Humain,Souris,Rat
Applications
IF/ICC, IHC, IP, WB
Host
Lapin
£278.80£328.00 Save 15%
Available to order
Comparing

Research context & evidence

About APC

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

APC is a core component of the beta-catenin destruction machinery and promotes CTNNB1/beta-catenin degradation when canonical Wnt signalling is inactive. APC also associates with cytoskeletal systems, contributing to cell polarity, migration and cellular organisation.

Experimental context

Research context

APC is widely studied in Wnt/beta-catenin signalling, epithelial homeostasis, cell polarity and Wnt-driven tumour biology. Use ABMIUM APC-associated products only after confirming the intended species, sample type, assay format, application and product-level validation.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Adenomatous polyposis coli proteinBTPS2DESMDDP2DP2.5DP3GSPPP1R46