ABMIUM target intelligence
angiopoietin like 4
ANGPTL4 (angiopoietin like 4), also known as angiopoietin-related protein 4 and FIAF, is a secreted glycoprotein studied for regulation of lipoprotein lipase, triglyceride clearance, lipid metabolism and metabolic homeostasis.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ANGPTL4 is a secreted regulator of lipid metabolism. Reviewed UniProt evidence shows that it inhibits lipoprotein lipase (LPL), limiting triglyceride hydrolysis and clearance of triglyceride-rich lipoproteins. Curated records also support roles in glucose homeostasis and insulin sensitivity, while the C-terminal region has reported effects on endothelial proliferation, migration and vascular permeability.
ANGPTL4 is studied in triglyceride metabolism, LPL regulation, fasting and nutrient-responsive metabolic biology, adipose and hepatic signalling, and endothelial responses. Reagent selection should remain product-specific: confirm species, sample type, assay format, application and validation rather than inferring experimental suitability from target biology alone.
Names used across publications, databases and supplier catalogues.
