ABMIUM target intelligence

ALPI

alkaline phosphatase, intestinal

Alkaline phosphatase, intestinal (ALPI), commonly called intestinal alkaline phosphatase (IAP), is a brush-border phosphomonoesterase expressed in the intestine. It is studied for its digestive phosphatase activity and its contribution to gut mucosal defence, including dephosphorylation of microbial products such as lipopolysaccharide.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene248 UniProtP09923

ABMIUM research catalogue

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Intestinal-type alkaline phosphataseIAPPPBIPPBI1

Biological function

Intestinal-type alkaline phosphatase (ALPI/IAP) hydrolyses phosphate monoesters and functions as a digestive brush-border enzyme. Authoritative records also support a role in gut mucosal defence, including detoxification of lipopolysaccharide and limitation of bacterial translocation.

Research context

ALPI/IAP is used in research on intestinal epithelial biology, brush-border enzyme function, host-microbe interactions and gut barrier defence. Use the catalogue filters below to compare ABMIUM ALPI-associated reagents and confirm species, application and product-level validation before use.