ABMIUM target intelligence
ATP binding cassette subfamily B member 1
ATP binding cassette subfamily B member 1 (ABCB1), widely known as P-glycoprotein 1, MDR1 or CD243, is an ATP-dependent membrane efflux transporter. This target record links verified nomenclature and ABMIUM catalogue products.
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Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ABCB1/P-glycoprotein is an ATP-dependent translocase that exports drugs, xenobiotics and selected phospholipids across membranes. Its efflux activity can reduce intracellular drug accumulation and is a major molecular mechanism associated with multidrug resistance.
ABCB1 is widely studied in membrane transport, pharmacology, drug disposition, blood-brain barrier biology and multidrug resistance. Reagent selection should consider species, cell or tissue context, membrane localization, application and product-level validation.
Names used across publications, databases and supplier catalogues.
