Potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFβ superfamily Type I activin receptor-like kinase). (ALK5 IC50 = 94 nM). Inhibits TGFβ-induced proliferation of human osteosarcoma cells. Ehances growth and integrity of embryonic stem cell-derived endothelial cells. A frequently used agent...
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Potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFβ superfamily Type I activin receptor-like kinase). (ALK5 IC50 = 94 nM). Inhibits TGFβ-induced proliferation of human osteosarcoma cells. Ehances growth and integrity of embryonic stem cell-derived endothelial cells. A frequently used agent employed in numerous stem cell differentiation protocols. Cell permeable
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