Originally thought to be a PARP1 inhibitor but this is controversial. Inhibits ionizing radiation-induced single-stranded DNA break repair in lymphoid cell lines in vivo. Inhibits growth of certain breast cancer cell lines in vitro. Non-selectively modifies cysteine-containing proteins in tumor...
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Originally thought to be a PARP1 inhibitor but this is controversial. Inhibits ionizing radiation-induced single-stranded DNA break repair in lymphoid cell lines in vivo. Inhibits growth of certain breast cancer cell lines in vitro. Non-selectively modifies cysteine-containing proteins in tumor cells
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PARP1 identifies poly(ADP-ribose) polymerase 1 in Homo sapiens (Human). This target record connects NCBI Gene 142, UniProtKB P09874 and related ABMIUM catalogue products.
