H-89 (127243-85-0) is a commonly used inhibitor of protein kinase A (PKA IC 50 = 140 nM). Inhibits a variety of other kinases including S6K1 (IC 50 = 80 nM), MSK1 (120 nM), ROCK II (270 nM), PKBα (2.6 µM), PKD, PRK2, RSK1 and 2, SGK, AMPK, CHK1 and MAPKAP-K1b (2.8 µM)
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H-89 (127243-85-0) is a commonly used inhibitor of protein kinase A (PKA IC 50 = 140 nM). Inhibits a variety of other kinases including S6K1 (IC 50 = 80 nM), MSK1 (120 nM), ROCK II (270 nM), PKBα (2.6 µM), PKD, PRK2, RSK1 and 2, SGK, AMPK, CHK1 and MAPKAP-K1b (2.8 µM)
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