Manufactured by:TriBio Science
RUO

GS-441524, Remdesivir active metabolite

Developed as an antiviral, with activity against HCV, YFV, DENV-2, influenza A, parainfluenza 3, and SARS-CoV. Also shown to be effective for feline infectious peritonitis. Notably the COVID-19 drug Remdesivir is rapidly metabolized in human serum to GS-441524, which shows comparable efficacy...

SKU:
ABM147090-1
Manufacturer SKU
TBI4485-25MG | TBI4485-5MG
Product type
Biochemical Inhibitors
TargetRemdesivir active metabolite
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Developed as an antiviral, with activity against HCV, YFV, DENV-2, influenza A, parainfluenza 3, and SARS-CoV. Also shown to be effective for feline infectious peritonitis. Notably the COVID-19 drug Remdesivir is rapidly metabolized in human serum to GS-441524, which shows comparable efficacy against SARS-CoV-2 in vitro, may reach the lungs more effectively, and has a better toxicity profile

Key facts & specifications
Also known as
(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
Molecular weight
291.30
Form / buffer
powder
Activity
Developed as an antiviral, with activity against HCV, YFV, DENV-2, influenza A, parainfluenza 3, and SARS-CoV. Also shown to be effective for feline infectious peritonitis. Notably the COVID-19 drug Remdesivir is rapidly metabolized in human serum to GS-441524, which shows comparable efficacy against SARS-CoV-2 in vitro, may reach the lungs more effectively, and has a better toxicity profile.
Molecular formula
C 12 H 13 N 5 O 4
Solubility
Soluble in DMSO (25 mg/ml)
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI4485-25MG | TBI4485-5MG
CAS number
1191237-69-0
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£237.00