Inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter. Undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1. Inhibits dengue virus infection in Huh-7 cells by...
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Inhibits cholesterol absorption in the intestine by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter. Undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1. Inhibits dengue virus infection in Huh-7 cells by blocking cholesterol transport. Ameliorates steatohepatitis by activation of autophagy and inhibition of NLRP3 inflammasome
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