Manufactured by:TriBio Science
RUO

Bedaquiline, Antituberculosis/SARS-CoV2 3CLpro inhibitor

Clinically useful antituberculosis agent that is active (MIC’s 0.030 to 0.120 µg/mL) against multi-drug resistant strains. It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE) and subunit ε of ATP synthase inhibiting ATP production. Bedaquiline has...

SKU:
ABM146688-1
Manufacturer SKU
TBI4403-25MG | TBI4403-5MG
Product type
Biochemical Inhibitors
TargetAntituberculosis/SARS-CoV2 3CLpro
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Clinically useful antituberculosis agent that is active (MIC’s 0.030 to 0.120 µg/mL) against multi-drug resistant strains. It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE) and subunit ε of ATP synthase inhibiting ATP production. Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 µM) of the SARS-CoV-2 main protease, 3CLpro

Key facts & specifications
Also known as
TMC207; R207910
Molecular weight
555.50
Form / buffer
powder
Activity
Clinically useful antituberculosis agent that is active (MIC’s 0.030 to 0.120 µg/mL) against multi-drug resistant strains. It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE) and subunit ε of ATP synthase inhibiting ATP production. Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 µM) of the SARS-CoV-2 main protease, 3CLpro.
Molecular formula
C 32 H 31 BrN 2 O 2
Solubility
Soluble in DMSO (up to 10 mg/ml)
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI4403-25MG | TBI4403-5MG
CAS number
843663-66-1
Storage, stability & shipping
Storage conditions
RT
Shipped at
4°C
Long-term storage
RT
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£270.00