Manufactured by:TriBio Science
RUO

BAY K8644, L-type calcium channel activator

BAY K8644 is an ionotropic agent that activates L-type calcium channels by prolonging single-channel open time without affecting closed time. It acts as a vasoconstrictor, and in combination with histone methyltransferase inhibitor BIX-01294 (#MC-1335), induces reprogramming of mouse embryonic...

SKU:
ABM146682-1
Manufacturer SKU
TBI4518-25MG | TBI4518-5MG
Product type
Biochemical Inhibitors
TargetL-type calcium channel
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

BAY K8644 is an ionotropic agent that activates L-type calcium channels by prolonging single-channel open time without affecting closed time. It acts as a vasoconstrictor, and in combination with histone methyltransferase inhibitor BIX-01294 (#MC-1335), induces reprogramming of mouse embryonic fibroblasts transduced with Oct4/Klf4

Key facts & specifications
Also known as
(±)- Methyl 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylate
Molecular weight
356.30
Form / buffer
powder
Activity
BAY K8644 is an ionotropic agent that activates L-type calcium channels by prolonging single-channel open time without affecting closed time. It acts as a vasoconstrictor, and in combination with histone methyltransferase inhibitor BIX-01294 (#MC-1335), induces reprogramming of mouse embryonic fibroblasts transduced with Oct4/Klf4.
Molecular formula
C 16 H 15 F 3 N 2 O 4
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI4518-25MG | TBI4518-5MG
CAS number
71145-03-4
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£409.00