Manufactured by:TriBio Science
RUO

BAM15, Mitochondrial oxidative phosphorylation inhibitor

Mitochondrial oxidative phosphorylation inhibitor A mitochondrial protonophore uncoupler with fewer off-target effects (EC50 = 270 nM in L6 myoblast mitochondria). Compared to FCCP, an uncoupler of equal potency, BAM15 stimulates a higher maximum rate of mitochondrial respiration and does not...

SKU:
ABM146672-1
Manufacturer SKU
TBI5104-25MG | TBI5104-5MG
Product type
Biochemical Inhibitors
TargetMitochondrial oxidative phosphorylation
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Mitochondrial oxidative phosphorylation inhibitor

A mitochondrial protonophore uncoupler with fewer off-target effects (EC50 = 270 nM in L6 myoblast mitochondria). Compared to FCCP, an uncoupler of equal potency, BAM15 stimulates a higher maximum rate of mitochondrial respiration and does not depolarize the plasma membrane. Stimulates energy expenditure, protects against obesity and improves glycemic control in rodent models. Reverses diet-induced obesity and insulin resistance in mice. Attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue

Key facts & specifications
Also known as
N5,N6-bis(2-Fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
Molecular weight
340.30
Form / buffer
powder
Activity
A mitochondrial protonophore uncoupler with fewer off-target effects (EC50 = 270 nM in L6 myoblast mitochondria). Compared to FCCP, an uncoupler of equal potency, BAM15 stimulates a higher maximum rate of mitochondrial respiration and does not depolarize the plasma membrane. Stimulates energy expenditure, protects against obesity and improves glycemic control in rodent models. Reverses diet-induced obesity and insulin resistance in mice. Attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.
Molecular formula
C 16 H 10 F 2 N 6 O
Solubility
Soluble in DMSO (up to at least 35 mg/ml)
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI5104-25MG | TBI5104-5MG
CAS number
210302-17-3
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£401.00