Manufactured by:TriBio Science
RUO

2GBI, Hv1 channel blocker

A selective and state-dependent blocker of voltage-gated proton channels (Hv1). 2GBI blocks the channel by binding to the voltage-sensing domain from its intracellular side. Inhibition of Hv1 is a potentially new target of intervention in various pathophysiological processes including...

SKU:
ABM146512-1
Manufacturer SKU
TBI3127-250MG | TBI3127-50MG
Product type
Biochemical Inhibitors
TargetHv1 channel blocker
Purity>95%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

A selective and state-dependent blocker of voltage-gated proton channels (Hv1). 2GBI blocks the channel by binding to the voltage-sensing domain from its intracellular side. Inhibition of Hv1 is a potentially new target of intervention in various pathophysiological processes including inflammatory, cancer, bone resorption and neurodegenerative disease

Key facts & specifications
Also known as
2-Guanidinobenzimidazole
Molecular weight
175.19
Form / buffer
powder
Activity
A selective and state-dependent blocker of voltage-gated proton channels (Hv1). 2GBI blocks the channel by binding to the voltage-sensing domain from its intracellular side. Inhibition of Hv1 is a potentially new target of intervention in various pathophysiological processes including inflammatory, cancer, bone resorption and neurodegenerative disease.
Molecular formula
C 8 H 9 N 5
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Water (up to 4 mg/ml with warming)
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI3127-250MG | TBI3127-50MG
CAS number
5418-95-1
Storage, stability & shipping
Storage conditions
RT
Shipped at
4°C
Long-term storage
RT
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
$196.00