Inhibits glutathione reductase and thioredoxin reductase, IC50s=6.7 and 8.7 µM respectively, and impairs mitochondrial function. May be used to induce a cellular model of thiol oxidative stress. Induces G2/M cell cycle arrest by inducing thiol oxidative stress resulting in α-tubulin...
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Inhibits glutathione reductase and thioredoxin reductase, IC50s=6.7 and 8.7 µM respectively, and impairs mitochondrial function. May be used to induce a cellular model of thiol oxidative stress. Induces G2/M cell cycle arrest by inducing thiol oxidative stress resulting in α-tubulin S-glutathionylation-mediated microtubule depolymerization. Improves limb revascularization by glutathionylation and subsequent stabilization of HIF-1α
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