IL18 polyclonal antibody; host Rabbit; reactivity Human, Rat, Mouse
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interleukin 18(IL18) Homo sapiens The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011],
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species / reactivity | WB IF | ELISA |
|---|---|---|
| Human,Rat,Mouse |
This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IL18 identifies interleukin 18 in Homo sapiens (Human). This target record connects NCBI Gene 3606, UniProtKB Q14116 and related ABMIUM catalogue products.
Biological function: IL18 is a pro-inflammatory cytokine involved in epithelial barrier repair and Th1 and natural-killer-cell immune responses. Signalling through IL18R1 and IL18RAP activates NF-kB and promotes inflammatory mediator production.
