DAPK1 polyclonal antibody; host Rabbit; reactivity Human, Mouse
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death associated protein kinase 1(DAPK1) Homo sapiens Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species / reactivity | WB | IHC-P | IF/ICC | ELISA |
|---|---|---|---|---|
| Human,Mouse |
This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Keratin 18 (KRT18), also known as cytokeratin 18, CK-18 and K18, is a type I cytoskeletal intermediate-filament protein. This ABMIUM target record connects NCBI Gene 3875 and UniProtKB P05783 to catalogue-backed research products.
Biological function: Keratin 18 (KRT18/CK-18) is a type I intermediate-filament protein expressed prominently in simple epithelial cells. It forms heteropolymeric filaments, notably with keratin 8, that contribute to cytoskeletal organisation, mechanical stability and epithelial-cell resilience.
