Manufactured by:Promab
RUO

Anti-SPAG8 Rabbit Polyclonal Antibody

SPAG8 antibody from Promab.

SKU:
ABM403367-1
Product type
Primary antibodies
TargetSPAG8
ApplicationsIHC
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. SPAG8 plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5-regulated transcriptional activation of CREM isoform tau. SPAG8 is involved in the acrosome reaction and in binding of sperm to the zona pellucida.

For research use only.

Key facts & specifications
Also known as
SMP1; BS-84; HSD-1; SPAG3; hSMP-1; SPAG8; sperm associated antigen 8
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
IHC
Immunogen
Fusion protein of human SPAG8
Technical note
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
SPAG8
Gene ID
26206
UniProt accession
Q99932
Ensembl
ENSG00000137098
HGNC
14105
OMIM
605731
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20