Manufactured by:Promab
RUO

Anti-SET1B Rabbit Polyclonal Antibody

SET1B antibody from Promab.

SKU:
ABM417619-1
Product type
Primary antibodies
TargetSET1B
ApplicationsWB
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

SETD1B is a histone methyltransferase that catalyses methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. SETD1B forms part of chromatin remodeling machinery, forms H3K4me1, H3K4me2 and H3K4me3 methylation marks at active chromatin sites where transcription and DNA repair take place. SETD1B plays an essential role in regulating the transcriptional programming of multipotent hematopoietic progenitor cells and lymphoid lineage specification during hematopoiesis.

For research use only.

Key facts & specifications
Also known as
Histone-lysine N-methyltransferase SETD1B; Lysine N-methyltransferase 2G; SET domain-containing protein 1B; hSET1B; SETD1B; KIAA1076; KMT2G; SET1B; SET domain containing 1B, histone lysine methyltransferase
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This SET1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1806-1839 amino acids from the C-terminal region of human SET1B.
Molecular weight
212.8 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
SETD1B
Gene ID
23067
UniProt accession
Q9UPS6
Ensembl
ENSG00000139718
HGNC
29187
OMIM
611055
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20