Manufactured by:Promab
RUO

Anti-Lfc Rabbit Polyclonal Antibody

Lfc antibody from Promab.

SKU:
ABM420104-1
Product type
Primary antibodies
TargetLfc
ApplicationsWB
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Activates Rho-GTPases by promoting the exchange of GDP for GTP. ARHGEF2 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. ARHGEF2 binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases, which was uniquely reported in PubMed:9857026.

For research use only.

Key facts & specifications
Also known as
ARHGEF2; KIAA0651; LFP40; Rho guanine nucleotide exchange factor 2; Guanine nucleotide exchange factor H1; GEF-H1; Microtubule-regulated Rho-GEF; Proliferating cell nucleolar antigen p40; Rho/Rac guanine nucleotide exchange factor 2; Lfc
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
Synthesized peptide derived from human Lfc around the non-phosphorylation site of S885.
Molecular weight
111 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
ARHGEF2
Gene ID
9181
UniProt accession
Q92974
Ensembl
ENSG00000116584
HGNC
682
OMIM
607560
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
$210.00