Manufactured by:Promab
RUO

Anti-IL27 Rabbit Polyclonal Antibody

IL27 antibody from Promab.

SKU:
ABM403180-1
Product type
Primary antibodies
TargetIL27
ApplicationsIHC
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Associates with EBI3 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17).

For research use only.

Key facts & specifications
Also known as
p28; IL30; IL-27; IL27A; IL27p28; interleukin 27; Interleukin-27 subunit alpha
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
IHC
Immunogen
Fusion protein of human IL27
Technical note
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
IL27
Gene ID
246778
UniProt accession
Q8NEV9
Ensembl
ENSG00000197272
HGNC
19157
OMIM
608273
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

IL27interleukin 27

View target guide

IL27 identifies interleukin 27 in Homo sapiens (Human). This target record connects NCBI Gene 246778, UniProtKB Q8NEV9 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
246778
UniProtKB
Q8NEV9
Promab
£174.20