Manufactured by:Promab
RUO

Anti-GNB5 Rabbit Polyclonal Antibody

GNB5 antibody from Promab.

SKU:
ABM403125-1
Product type
Primary antibodies
TargetGNB5
ApplicationsWB, IHC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Enhances GTPase-activating protein (GAP) activity of regulator of G protein signalling (RGS) proteins, such as RGS7 and RGS9, hence involved in the termination of the signalling initiated by the G protein-coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation. Increases RGS7 GTPase-activating protein (GAP) activity, thereby regulating mood and cognition. Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signalling initiated by D(2) dopamine receptors.

For research use only.

Key facts & specifications
Also known as
GB5; GNB5; G protein subunit beta 5; Guanine nucleotide-binding protein subunit beta-5
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB,IHC
Immunogen
Fusion protein of human GNB5
Molecular weight
44 kDa
Technical note
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
GNB5
Gene ID
10681
UniProt accession
O14775
Ensembl
ENSG00000069966
HGNC
4401
OMIM
604447
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20