CD5 antibody from Promab.
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Lymphoid-specific receptor expressed by all T-cells and in a subset of B-cells known as B1a cells. CD5 plays a role in the regulation of TCR and BCR signalling, thymocyte selection, T-cell effector differentiation and immune tolerance. CD5 acts by interacting with several ligands expressed on B-cells such as CD5L or CD72 and thereby plays an important role in contact-mediated, T-dependent B-cell activation and in the maintenance of regulatory T and B-cell homeostasis.
For research use only.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP | ChIP |
|---|---|---|---|---|---|---|---|---|---|
| Human | |||||||||
| Mouse | |||||||||
| Rat |
This product is manufactured by Promab and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CD5 molecule (CD5), also called T-cell surface glycoprotein CD5 and historically LEU1/T1, is a cell-surface receptor expressed on T cells and subsets of B cells. ABMIUM catalogue products linked below support research on CD5 biology.
Biological function: CD5 molecule (CD5) is a type I transmembrane glycoprotein expressed on thymocytes, mature T cells and a subset of B cells. It participates in lymphocyte signalling and can modulate antigen-receptor responses and T-cell proliferation, making CD5 a widely used target in immune-cell and lymphocyte research.
