Manufactured by:ProteoGenix
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Zubotamig Biosimilar – Anti-VTCN1;CD3e mAb – Research Grade

Zubotamig Biosimilar – Anti-VTCN1;CD3e mAb – Research Grade from ProteoGenix; catalogue PX-TA2190; research use only.

SKU:
ABM133860-1
Manufacturer SKU
PX-TA2190
Product type
Primary Antibodies
TargetZubotamig Biosimilar – Anti-VTCN1;CD3e mAb – Research Grade
ApplicationsELISA
Expression systemXtenCHO
Purity>95% by SDS-PAGE

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Zubotamig Biosimilar – Anti-VTCN1;CD3e mAb – Research Grade

Introduction

Zubotamig Biosimilar – Anti-VTCN1;CD3e mAb – Research Grade is a therapeutic antibody that has shown promising results in targeting and treating various diseases. This biosimilar is a highly specific and potent monoclonal antibody that has been designed to mimic the activity of the original therapeutic antibody, but at a more affordable cost.

Structure of Zubotamig Biosimilar

Zubotamig Biosimilar is a monoclonal antibody, which means it is derived from a single clone of cells. It is a protein molecule composed of two identical heavy chains and two identical light chains, connected by disulfide bonds. These chains are further divided into constant and variable regions, with the variable regions being responsible for binding to the target molecule.

Activity of Zubotamig Biosimilar

Zubotamig Biosimilar targets a protein called VTCN1, also known as B7-H4, which is overexpressed in various cancer cells. This protein plays a crucial role in suppressing the immune response against cancer cells, allowing them to evade detection and destruction by the immune system. By binding to VTCN1, Zubotamig Biosimilar blocks its activity and restores the immune response, leading to the destruction of cancer cells.

Application of Zubotamig Biosimilar

Zubotamig Biosimilar has shown promising results in preclinical and clinical studies for the treatment of various cancers, including breast, lung, ovarian, and bladder cancer. It has also shown potential in treating autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, as well as infectious diseases such as HIV and hepatitis B.

Therapeutic Antibody for Cancer Treatment

Zubotamig Biosimilar is a highly specific and potent therapeutic antibody that has been specifically designed for the treatment of cancer. It has shown promising results in both in vitro and in vivo studies, with minimal side effects. It has the potential to become a more affordable alternative to the original therapeutic antibody, making it more accessible to patients.

Therapeutic Target: VTCN1

VTCN1 is a protein that is overexpressed in various cancer cells. It plays a crucial role in suppressing the immune response against cancer cells, allowing them to evade detection and destruction by the immune system. By targeting VTCN1, Zubotamig Biosimilar helps to restore the immune response and destroy cancer cells.

Research Grade Antibody

Zubotamig Biosimilar is a research grade antibody, meaning it is primarily used for research purposes and not yet approved for clinical use. However, it has shown promising results in preclinical and clinical studies and is currently undergoing further research and development for potential approval as a therapeutic antibody.

Conclusion

Zubotamig Biosimilar – Anti-VTCN1;CD3e mAb – Research Grade is a highly specific and potent monoclonal antibody that has shown promising results in targeting and treating various diseases, particularly cancer. Its unique structure and mechanism of action make it a promising candidate for the treatment of various cancers, autoimmune diseases, and infectious diseases. Further research and development are underway to potentially approve this biosimilar as a more affordable and accessible therapeutic antibody.

ProteoGenix catalogue number PX-TA2190. For research use only.

Target: Zubotamig Biosimilar – Anti-VTCN1;CD3e mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE; Buffer: 0.01M PBS, pH 7.4; Applications: ELISA.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
anti-V-set domain-containing T-cell activation inhibitor 1, B7h.5, B7 homolog 4, B7-H4, T-cell costimulatory molecule B7x, B7H4, VTCN1, Protein B7S1, Immune costimulatory protein B7-H4, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Clonality
Monoclonal
Isotype
Ig (H-gamma1_L-kappa)_(H-gamma1_Llambda2)
Source organism
Human
Sequence
MASLGQILFWSIISIIIILAGAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTFEPDIKLSDIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNVQLTDAGTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKVTESEIKRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLMLK
Technical note
For research use only. Not suitable for human use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Zubotamig Biosimilar – Anti-VTCN1;CD3e mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA2190
UniProt accession
Q7Z7D3 & P07766
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£149.00£119.20