Manufactured by:ProteoGenix
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Uliledlimab Biosimilar – Anti-NT5E mAb – Research Grade

Uliledlimab Biosimilar – Anti-NT5E mAb – Research Grade from ProteoGenix; catalogue PX-TA1730; research use only.

SKU:
ABM134318-1
Manufacturer SKU
PX-TA1730
Product type
Primary Antibodies
TargetUliledlimab Biosimilar – Anti-NT5E mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction

Uliledlimab Biosimilar, also known as Anti-NT5E mAb, is a monoclonal antibody that targets the enzyme CD73, also known as NT5E. This enzyme is involved in the production of adenosine, a molecule that plays a key role in regulating the immune response. By inhibiting CD73, Uliledlimab Biosimilar has the potential to modulate the immune system and treat various diseases. In this article, we will explore the structure, activity, and potential applications of Uliledlimab Biosimilar as a research grade antibody.

Structure of Uliledlimab Biosimilar

Uliledlimab Biosimilar is a fully human monoclonal antibody, meaning it is derived from human cells and has a high level of specificity and affinity for its target. It is composed of two identical heavy chains and two identical light chains, each containing a variable region that binds specifically to CD73. The structure of Uliledlimab Biosimilar is similar to that of other therapeutic antibodies, with a Y-shaped structure and a flexible hinge region that allows for binding to multiple targets.

Activity of Uliledlimab Biosimilar

The main activity of Uliledlimab Biosimilar is its ability to inhibit the activity of CD73. This enzyme is expressed on the surface of various immune cells, including T cells, B cells, and natural killer cells. CD73 is responsible for converting extracellular ATP to adenosine, which has immunosuppressive effects. By inhibiting CD73, Uliledlimab Biosimilar can prevent the production of adenosine and potentially enhance the immune response.

Additionally, Uliledlimab Biosimilar has been shown to have anti-inflammatory effects by reducing the production of pro-inflammatory cytokines and chemokines. This activity has been demonstrated in various pre-clinical studies, making Uliledlimab Biosimilar a promising candidate for the treatment of inflammatory diseases.

Potential Applications of Uliledlimab Biosimilar

As a research grade antibody, Uliledlimab Biosimilar has the potential to be used in a variety of studies and experiments. Its main application is in the field of immunology, where it can be used to investigate the role of CD73 in the immune response and its potential as a therapeutic target.

Uliledlimab Biosimilar may also have potential applications in the treatment of various diseases. Its ability to modulate the immune response could make it a valuable tool in the treatment of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Additionally, its anti-inflammatory effects could be beneficial in the treatment of inflammatory conditions, such as asthma and inflammatory bowel disease.

Furthermore, Uliledlimab Biosimilar has shown promising results in pre-clinical studies for the treatment of cancer. By inhibiting CD73, it can prevent the production of adenosine, which is known to suppress the immune response against tumors. This makes Uliledlimab Biosimilar a potential candidate for combination therapy with other cancer treatments.

Conclusion

In summary, Uliledlimab Biosimilar is a monoclonal antibody that targets CD73 and has the potential to modulate the immune response and treat various diseases. Its structure, activity, and potential applications make it a valuable tool for research and a promising candidate for therapeutic use. Further studies and clinical trials are needed to fully understand the potential of Uliledlimab Biosimilar as a therapeutic antibody.

ProteoGenix catalogue number PX-TA1730. For research use only.

Target: Uliledlimab Biosimilar – Anti-NT5E mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Uliledlimab,IMMUNOGLOBULIN G1 (300-ALANINE), ANTI-(HUMAN CD73 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL TJ004309 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL TJ004309 .KAPPA.-CHAIN, DIMER, TJ-D5,NT5E,anti-NT5E
Clonality
Monoclonal
Isotype
IgG1,Kappa
Source organism
CAS 2378407-27-1
Sequence
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFSTGSHCHGSFSLIFLSLWAVIFVLYQ
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Uliledlimab Biosimilar – Anti-NT5E mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1730
UniProt accession
P21589
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
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