Tuvirumab Biosimilar – Anti-HBV mAb – Research Grade from ProteoGenix; catalogue PX-TA1124; research use only.
Know who made it. See the evidence. Buy through one marketplace.
Tuvirumab Biosimilar is a monoclonal antibody (mAb) that has been developed as a biosimilar to the anti-hepatitis B virus (HBV) mAb, Tuvirumab. It is a recombinant humanized IgG1 mAb that has been engineered to target the HBV surface antigen (HBsAg). The mAb is composed of two heavy chains and two light chains, each with a molecular weight of approximately 150 kDa. The heavy chains consist of four constant domains (CH1, CH2, CH3, and CH4) and one variable domain (VH), while the light chains consist of two constant domains (CL and CL’) and one variable domain (VL). The variable domains of the heavy and light chains form the antigen-binding site of the mAb, which is responsible for its specificity and binding to HBsAg.
Tuvirumab Biosimilar has been shown to have high affinity and specificity for HBsAg, making it a potent inhibitor of the HBV virus. The mAb binds to the HBsAg on the surface of the virus, preventing its entry into host cells and inhibiting its replication. This activity has been demonstrated in both in vitro and in vivo studies, showing the potential of Tuvirumab Biosimilar as an effective therapeutic agent for HBV infection.
In addition to its direct antiviral activity, Tuvirumab Biosimilar also has immunomodulatory effects. It has been shown to enhance the host immune response against HBV by promoting the production of neutralizing antibodies and activating immune cells, such as natural killer cells and T cells. This dual mechanism of action makes Tuvirumab Biosimilar a promising candidate for the treatment of HBV infection.
Tuvirumab Biosimilar is currently being developed as a research grade mAb for the treatment of chronic HBV infection. It is intended to be used as a monotherapy or in combination with other antiviral agents for the management of HBV infection. The mAb has shown promising results in preclinical studies, and clinical trials are currently underway to evaluate its safety and efficacy in patients with chronic HBV infection.
In addition to its potential use as a therapeutic agent, Tuvirumab Biosimilar also has applications in diagnostic and research settings. The mAb can be used in diagnostic assays to detect and quantify HBsAg in patient samples, providing a valuable tool for the diagnosis and monitoring of HBV infection. It can also be used in research studies to further understand the mechanisms of HBV infection and to develop new treatments for the disease.
Tuvirumab Biosimilar has the potential to become a valuable addition to the current treatment options for chronic HBV infection. Its unique mechanism of action and dual activity make it a promising candidate for the management of this disease. With ongoing clinical trials and further research, Tuvirumab Biosimilar may soon become a widely used therapeutic agent for HBV infection.
In conclusion, Tuvirumab Biosimilar is a recombinant humanized mAb that targets HBsAg and has shown potent antiviral and immunomodulatory activity in preclinical studies. It is being developed as a research grade mAb for the treatment of chronic HBV infection and has potential applications in diagnostics and research. With its promising results and ongoing development, Tuvirumab Biosimilar has the potential to improve the treatment and management of HBV infection in the future.
ProteoGenix catalogue number PX-TA1124. For research use only.
Target: Tuvirumab Biosimilar – Anti-HBV mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Tuvirumab Biosimilar – Anti-HBV mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
