Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb – Research Grade from ProteoGenix; catalogue PX-TA2087; research use only.
Know who made it. See the evidence. Buy through one marketplace.
Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb – Research Grade: A Revolutionary Antibody Therapy for Canine Lupus Canine lupus, also known as systemic lupus erythematosus (SLE), is a chronic autoimmune disease that affects dogs. It is characterized by the production of autoantibodies, which attack the body’s own tissues and organs, leading to inflammation and tissue damage. Canine lupus can affect multiple organs, including the skin, joints, kidneys, and blood vessels, and can be life-threatening if left untreated. Currently, there is no cure for canine lupus, and treatment options are limited. However, a new and innovative therapy, Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb – Research Grade, has emerged as a potential game-changer in the treatment of this debilitating disease.
Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb is a biosimilar antibody therapy that is designed to specifically target interleukin-31 (IL-31), a cytokine that plays a crucial role in the development and progression of canine lupus. IL-31 is produced by immune cells and is known to promote inflammation and itchiness in the skin, which are common symptoms of canine lupus. Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb is a monoclonal antibody, meaning it is produced by a single clone of immune cells, and is designed to bind to and neutralize IL-31, thereby reducing its inflammatory effects.
The structure of Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb is similar to that of the natural antibodies found in the canine immune system. It is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The antibody also contains a variable region that is responsible for binding to IL-31 and a constant region that is responsible for activating the immune system to destroy the bound IL-31. This unique structure allows Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb to effectively target and neutralize IL-31, providing relief from the symptoms of canine lupus.
Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb has been extensively studied and has shown promising results in pre-clinical trials. In a study conducted on dogs with naturally occurring lupus, treatment with Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb resulted in a significant reduction in skin lesions, joint inflammation, and kidney damage. The antibody was also found to improve the overall quality of life of the dogs, with reduced itching and pain. These results suggest that Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb has the potential to be a highly effective therapy for canine lupus.
In addition to its anti-inflammatory effects, Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb also has immunomodulatory properties. This means that it can regulate the activity of the immune system, preventing it from attacking the body’s own tissues. This is a crucial aspect of treating autoimmune diseases like canine lupus, where the immune system is overactive and causes damage to healthy tissues. By targeting IL-31, Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb not only reduces inflammation but also helps to restore the balance of the immune system, providing a more comprehensive treatment approach.
Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb is currently being developed as a research-grade therapy
ProteoGenix catalogue number PX-TA2087. For research use only.
Target: Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >90% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA, WB.
Available configurations: 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
